BDBM144315 Gilteritinib::US11512074, Example T-9::US8969336, 547::US8969336, 577
SMILES CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1
InChI Key InChIKey=GYQYAJJFPNQOOW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 144315
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of N-terminal GST-tagged human AXL (464 to 885 residues) cytoplasmic domain expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of AXL (unknown origin) using poly (Glu, Tyr) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 7.46nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 7.35nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 7.01nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 6.62nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 5.87nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 5.33nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 5.15nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 6.24nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:The test compounds were dissolved in DMSO, and subjected to a 3-fold serial gradient dilution for 10 times. AXL kinase was transferred with different...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of AXL (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Binding affinity towards rat beta adrenergic receptor from heart membranes.More data for this Ligand-Target Pair